The NPM1-ALK Fusion/Translocation FISH Probe Kit is designed to detect rearrangements involving the human NPM1 and ALK genes located on chromosome bands 5q35.1 and 2p23.2, respectively.
Rearrangements between the two genes, the NPM1 gene – also called B23 or NPM – and the ALK gene – also known as CD246 or NBLST3, have been observed in anaplastic large cell lymphoma and other myeloid malignancies.
