The MECOM/CCP3 FISH Probe Kit is designed to detect the human MECOM locus located on chromosome band 3q26.2, along with the number of chromosome 3 copies per cell.
Rearrangements and abnormal expression of the MECOM gene – also known as EVI1, MDS1, PRDM3, MDS1-EVI1 or AML1-EVI-1 – have been observed in acute and chronic myelogenous leukemias, Myelodysplastic Syndrome (MDS) and other malignancies.