The FGFR1 Break Apart FISH Probe Kit is designed to detect rearrangements in the human FGFR1 gene located on chromosome band 8p11.23.
In addition to revealing breaks, which can lead to translocation of parts of the gene, inversion, or its fusion to other genes, the probe set can also be used to identify other FGFR1 aberrations such as deletions or amplifications.
Rearrangements and abnormal expression of the FGFR1 gene – also known as CEK, FLG, HH2, OGD, FLT2, KAL2, BFGFR, CD331, FGFBR, FLT-2, HBGFR, N-SAM, FGFR-1, HRTFDS or bFGF-R-1 – have been observed in a large number of hematological and solid tumor types, and other conditions.
