The CARS/CCP11 FISH Probe Kit is designed to detect the human CARS gene located on chromosome band 11p15.4, along with the number of chromosome 11 copies per cell.
Rearrangements and abnormal expression of the CARS gene – also known as CARS1, CYSRS or MGC:11246 – have been observed in inflammatory myofibroblastic tumors (IMT) and several other tumor types.