The MNX1 Break Apart FISH Probe Kit is designed to detect rearrangements in the humanMNX1gene mapping to chromosome band 7q36.3.
In addition to revealing breaks, which can lead to translocation of parts of the gene, inversion, or its fusion to other genes, the probe set can also be used to identify otherMNX1aberrations such as deletions or amplifications.Rearrangements and abnormal expression of theMNX1gene – also known as HB9, HLXB9, SCRA1 or HOXHB9 - have been observed in acute myeloid leukemia （AML） and other tumor types.
