The TP73/ABL2, GLTSCR1/ZNF443 FISH Probe Kit is designed to simultaneously detect rearrangements involving the human TP73 and ABL2 genes, located on chromosome bands 1p36.32 and 1q25.2, respectively, and the human GLTSCR1 (19q13.33) and ZNF443 (19p13.2) genes.
Deletions and other abnormalities of these regions have been observed in gliomas, astrocytomas and various other malignancies.