The IPO11/AHRR FISH Probe Kit is designed to detect the human IPO11 gene located on chromosomes band 5q12.1, along with the AHRR gene region on chromosome band 5p15.33 as a control for integrity of the 5p subtelomeric region.
Rearrangements and abnormal expression of the IPO11 gene – also known as RanBP11 – have been observed in bladder cancer and other tumor types.