The CISD2/CCP4 FISH Probe Kit is designed to detect the human CISD2 gene located on chromosome band 4q24, along with the number of chromosome 4 copies per cell.
Abnormalities in CISD2 – also known as ERIS, WFS2, ZCD2, NAF-1 or Miner1 – have been observed in liver cancer and other malignancies.
The gene has been associated with Wolfram Syndrome.