The TERC/PTGS2/CCP7 FISH Probe Kit is designed to detect the human TERC and PTGS2 genes located on chromosome band 3q26.2 and 1q31.1, respectively, along with the number of chromosome 7 copies per cell.
Abnormal expression of both genes (TERC – also known as TR, hTR, TRC3, DKCA1, PFBMFT2 or SCARNA19 – and PTGS2 – also known as COX2, COX-2, PHS-2, PGG/HS, PGHS-2, hCox-2 or GRIPGHS) has been observed in cervical carcinoma, various other solid tumor types, and other conditions.