The TERC/TERT/CCP7 FISH Probe Kit is designed to detect the human TERC and TERT genes located on chromosome band 3q26.2 and 5p15.33, respectively, along with the number of chromosome 7 copies per cell.
Abnormal expression of both genes (TERC – also known as TR, hTR, TRC3, DKCA1, PFBMFT2 or SCARNA19 – and TERT – also known as TP2, TRT, CMM9, EST2, TCS1, hTRT, DKCA2, DKCB4, hEST2 or PFBMFT1) has been observed in cervical carcinoma and a variety of other tumor types.