83-2272-61　［受注停止］KRIBIOLISA Ubamatamab ELISA 1 x 96 wells　KBI1771

特徴

• Description：ELISA for the detection of bispecific antibody Ubamatamab in human serum and plasma.
• Lead time for this kit is 5 weeks.
• About the kit： - Uses anti-idiotypic monoclonal antibodies sourced from our vendor partner in the US, which ensures higher specificity, and low cross reactivity.
• - Recovery rates are between 85 - 115％ - Validated as per US FDA guidelines for Bioassays - Developed using the innovator drug as calibrator - Shelf life： 1 year.Ubamatamab is a human bispecific antibody designed to bridge MUC16 on cancer cells with CD3-expressing T cells to facilitate T-cell activation and cytotoxicity.
• It is designed to trigger rapid internalization of this complex into cancer cells to degrade the MET receptor and block its ability to support cell proliferation.
• Preclinical models examining immune-deficient mice have shown that ubamatamab combined with human immune cells led to dose-dependent antitumor activity against intraperitoneal MUC16-expressing ovarian tumor cells and malignant ascites.
• Preclinical trials are currently ongoing.