Description:ELISA for the detection of Tarlatamab in human serum and plasma.
Lead time for this kit is 5 weeks.
About the kit: - Uses anti-idiotypic monoclonal antibodies sourced from our vendor partner in the US, which ensures higher specificity, and low cross reactivity.
- Recovery rates are between 85 - 115% - Validated as per US FDA guidelines for Bioassays - Developed using the innovator drug as calibrator - Shelf life: 1 year.
Tarlatamab is an HLE BiTE immuno-oncology therapy designed to bind DLL3 on target cancer cells and CD3 on T cells, forming a cytolytic synapse inducing T cell activation and expansion and T cell-dependent killing of tumor cells.
Delta-like ligand 3 (DLL3) is a Notch ligand that is upregulated and aberrantly expressed on the cell surface in most Small Cell Lung Cancer, making it a compelling therapeutic target.
Phase I trials have shown promising results - tarlatamab was reasonably effective and had manageable levels of toxicity.
仕様
サイズ:1 x 96 wells
Reactivity:Human
アプリケーション:ELISA,Immunoassay
Sensitivity:Please refer to the current IFU for the updated calibrator range and sensitivity.