Description:ELISA for the detection of bispecific antibody Cevostamab in human serum and plasma.
Lead time for this kit is 5 weeks.
About the kit: - Uses anti-idiotypic monoclonal antibodies sourced from our vendor partner in the US, which ensures higher specificity, and low cross reactivity.
- Recovery rates are between 85 - 115% - Validated as per US FDA guidelines for Bioassays - Developed using the innovator drug as calibrator - Shelf life: 1 year.Cevostamab is a bispecific antibody, designed for the treatment of multiple myeloma.
It binds to both the CD3 antigen on cytotoxic T lymphocytes (CTLs) and FCRH5 found on FCRH5-expressing tumor cells.
This activates and crosslinks CTLs with FCRH5-expressing tumor cells, which results in the CTL-mediated cell death of FCRH5-expressing tumor cells.
FCRH5, an immune receptor translocation-associated protein/Fc receptor homolog (IRTA/FCRH) family member and a B-cell lineage marker, is overexpressed on myeloma cells.
仕様
サイズ:1 x 96 wells
Reactivity:Human
アプリケーション:ELISA,Immunoassay
Sensitivity:Please refer to the current IFU for the updated calibrator range and sensitivity.