83-2271-82　［受注停止］KRISHZYME Enoxaparin Factor IIa Assay Kit 100 tests / 1 kit　KBBA03ES

特徴

• Description：Chromogenic assay for testing Enoxaparin in purified systems by measurement of
• factor IIa inhibition, in compliance with pharmacopoeias （EP/BP） and FDA guidelines
• About the kit：
• - Uses anti-idiotypic antibodies sourced from our vendor partner in the US, which ensures higher specificity, and low cross reactivity.
• - Recovery rates are between 85 - 115％
• - Ready to use with a standard protocol with break-apart pre-coated wells
• - Validated as per US FDA guidelines for Bioassays
• - Optimized for matrix effects to ensure higher sensitivity.
• - Shelf life： 1 year
• The inhibitory effect of anti-thrombin III （AT-III） on thrombin, factor IIa and other coagulation serine proteases in
• plasma is increased several thousand-fold by enoxaparin.
• This inhibition accounts for the anticoagulant effect of
• enoxaparin.
• The quantitative determination of enoxaparin levels by the measurement of their anti-IIa activity is a
• necessary tool for monitoring treatment efficacy.
• Presence of Enoxaparin catalyzes the reaction between AT lll and α-Thrombin.
• The factor IIa inhibition test is the
• most useful assay covering the widest variety of enoxaparin preparations.
• In the assay, the rate of factor IIa
• inhibition is directly proportional to the enoxaparin concentration since both factor IIa and AT-III are in excess.
• The
• residual factor IIa activity is inversely proportional to the enoxaparin concentration.