83-1198-75　Recombinant Human Calnexin Protein （C-His） 1mg　BP275-1mg

特徴

• 背景：Calnexin/CANX is a single-pass type I membrane protein which belongs to the calreticulin family. It consists of a large N-terminal calcium-binding lumenal domain, a single transmembrane helix and a short （90 residues）, acidic cytoplasmic tail. The function of calnexin is to retain unfolded or unassembled Nlinked glycoproteins in the endoplasmic reticulum. Calnexin is a calcium-binding protein that interacts briefly with newly synthesized glycoproteins in the endoplasmic reticulum. Calnexin may act in assisting protein assembly and/or in the retention within the ER of unassembled protein subunits. Calnexin seems to play a major role in the quality control apparatus of the ER by the retention of incorrectly folded proteins. Calnexin dwindles with aging and might contribute to a cytoprotection in an array of human agerelated diseases.

仕様

• サイズ：1mg
• 種由来：Human
• 発現宿主：Human 293 Cells
• エンドトキシン：Less than 0.1 EU/ug
• タグ：C-6His
• Target Sequence：His21-Pro481
• FormulationSupplied as a 0.2 um filtered solution of 20mM Tris-HCl, 150mM NaCl, 2mM CaCl2, 10％ Glycerol, pH7.5
• Accession 番号：P27824
• この商品は法規制を確認しておりません。（法規制によって販売できない場合もございます）

• 【試薬に関するお問合せ】
• アズワン株式会社 試薬・プロセス材料グループ
• TEL：06-6447-8641
• FAX：06-6447-8642
• E-mail：[email protected]