83-1198-49 Recombinant Cynomolgus GUCY2C (C-hFc) 500ug BP266-500ug
特徴
- 背景:GUCY2C (Guanylyl Cyclase C), also known as heat-stable enterotoxin receptor, is a type I transmembrane protein of the guanylate cyclase (gc) family that signal by producing cGMP. Guanylate cyclase C (GUCY2C) and its hormones guanylin and uroguanylin have recently emerged as one paracrine axis defending intestinal mucosal integrity against mutational, chemical, and inflammatory injury. GUCY2C murine CAR-T cells recognized and killed human colorectal cancer cells endogenously expressing GUCY2C. Thus, we have identified a human GUCY2C-specific CAR-T cell therapy approach that may be developed for the treatment of GUCY2C-expressing metastatic colorectal cancer.
仕様
- サイズ:500ug
- 種由来:Cynomolgus
- 発現宿主:Human 293 Cells
- エンドトキシン:Less than 0.1 EU/ug
- タグ:C-hFc
- Target Sequence:Ser24-Gln430
- FormulationLyophilized from a 0.2 um filtered solution of PBS,pH7.4
- Accession 番号:G7PJX5
- この商品は法規制を確認しておりません。(法規制によって販売できない場合もございます)
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- アズワン株式会社 試薬・プロセス材料グループ
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商品のバリエーション (サイズ違い・スペック違い・オプション品など)
| 商品イメージ | アズワン品番 商品名 |
|---|---|
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83-1198-33
Recombinant Cynomolgus GUCY2C (C-hFc) 50ug
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83-1198-17
Recombinant Cynomolgus GUCY2C (C-hFc) 10ug
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83-1198-65
Recombinant Cynomolgus GUCY2C (C-hFc) 1mg
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83-1198-49
Recombinant Cynomolgus GUCY2C (C-hFc) 500ug
|
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