83-1174-71　Recombinant Human CD19 protein （C-hFc） 50ug　BP225-50ug

特徴

• 背景：CD19 is a single-pass type I membrane protein containing 2 Ig-like C2-type （immunoglobulin-like） domains. CD19 is expressed on follicular dendritic cells and B cells. In fact, it is present on B cells from earliest recognizable B-lineage cells during development to B-cell blasts but is lost on maturation to plasma cells. CD19 primarily acts as a B cell co-receptor in conjunction with CD21 and CD81. Upon activation, the cytoplasmic tail of CD19 becomes phosphorylated, which leads to binding by Src-family kinases and recruitment of PI-3 kinase. CD19 Assembles with the antigen receptor of B lymphocytes in order to decrease the threshold for antigen receptor-dependent stimulation.

仕様

• サイズ：50ug
• 種由来：Human
• 発現宿主：Human 293 Cells
• エンドトキシン：Less than 0.1 EU/ug
• タグ：C-hFc
• Target Sequence：Pro20-Lys291
• FormulationLyophilized from a 0.2 um filtered solution of 20mM PB, 150mM NaCl, pH 7.4
• Accession 番号：P15391
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