83-1174-21　Recombinant Human IGFBP-7 （C-His） 1mg　BP209-1mg

特徴

• 背景：Insulin-like growth factor-binding protein 7（IGFBP-7） is a secreted glycosylated protein that is a member of the insulin-like growth factor （IGF） binding proteins superfamily. IGFBP7 contains an N-terminal IGFBP domain, followed by a Kazal-type serine proteinase inhibitor domain and a C-terminal immunoglobulin-like C2-type domain. IGFBP7 is expressed in multiple normal tissues as well as cancer cells. It is highly expressed in high endothelial venules （HEVs） of blood vessels in the secondary lymphoid tissues. IGFBP7 interacts with heparan sulfate proteoglycans, type IV collagen, and specific chemokines. It supports weak cell adhesion, facilitates cell spreading on type IV collagen, and stimulates the production of the potent vasodilator PGI2. In addition, IGFBP7 modulates tumor cell growth and has also been implicated in angiogenesis.

仕様

• サイズ：1mg
• 種由来：Human
• 発現宿主：Human 293 Cells
• エンドトキシン：Less than 0.1 EU/ug
• タグ：C-6His
• Target Sequence：Ser27-Leu282
• FormulationLyophilized from a 0.2 um filtered solution of PBS, 0.05％Tween 80, pH7.4
• Accession 番号：Q16270
• この商品は法規制を確認しておりません。（法規制によって販売できない場合もございます）

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