83-1173-79　Recombinant Human Interleukin-36 gamma/IL-36G 500ug　BP206-500ug

特徴

• 背景：Interleukin-36 gamma （IL-36γ） belongs to the interleukin 1 cytokine family that includes three closely related genes, IL-36α, β, and γ, formerly known as IL-1F6, F8, and F9 respectively. IL-36α has been found in both neuronal and synovial tissue, while IL-36β and IL-36γ are expressed in both cutaneous and mucosal epithelial cells of the respiratory tract. IL-36β and IL-36γ facilitate proliferation, maturation, and cytokine expression by innate immune cells （such as keratinocytes and dendritic cells）, and adaptive immune cells （neutrophils and T-cells） in both humans and mice. The activity of IL-36α is mediated by interleukin 1 receptor-like 2 （IL1RL2/IL1R-rp2） and is specifically inhibited by interleukin 1 family, member 5 （IL1F5/IL-1 delta）. IL-36γ plays an essential role in communicating cell death to surrounding cells.

仕様

• サイズ：500ug
• 種由来：Human
• 発現宿主：E.coli
• エンドトキシン：Less than 1 EU/ug
• タグ：tag free
• Target Sequence：Ser18-Asp169
• FormulationLyophilized from a 0.2 um filtered solution of 20mM Tris, 100mM NaCl, 0.1mM EDTA, pH8.0
• Accession 番号：Q9NZH8
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