83-1172-99　Recombinant Human IL-23 （C-His） 10ug　BP199-10ug

特徴

• 背景：Interleukin 23 （IL-23） is a member of the IL-12 family of cytokines. IL-23 is a heterodimeric cytokine composed of two disulfide-linked subunits, a p19 subunit that is unique to IL-23, and a p40 subunit that is shared with IL-12. The p19 subunit has homology to the p35 subunit of IL-12, as well as to other single-chain cytokines such as IL-6 and IL-11. The p40 subunit is homologous to the extracellular domains of the hematopoietic cytokine receptors. While p19 is expressed by activated macrophages, dendritic cells, T cells, and endothelial cells, p40 is only expressed by activated macrophages and dendritic cells. Both IL-12 and IL-23 induce proliferation and IFN-gamma production by human T cells. While IL-12 acts on both naive and memory human T cells, the effects of IL-23 is restricted to memory T cells.

仕様

• サイズ：10ug
• 種由来：Human
• 発現宿主：Human 293 Cells
• エンドトキシン：Less than 0.1 EU/ug
• タグ：C-6His
• Target Sequence：Arg20-Pro189 ＆ Ile23-Ser328
• FormulationLyophilized from a 0.2 um filtered solution of PBS, 0.01％Tween 80, pH7.4
• Accession 番号：Recombinant IL-23 subunit alpha （C-His）
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