83-1172-80　Recombinant Human IL-3R alpha/CD123（C-hFc） 10ug　BP123-10ug

特徴

• 背景：CD123, also known as Interleukin-3 receptor subunit alpha, is a glycoprotein that belongs to the type I cytokine receptor family. CD123 is a heterodimer with an alpha and a beta subunit. The alpha subunit alone binds IL‑3 with low affinity. The beta subunit does not bind IL‑3 by itself but is required for the high‑affinity binding of IL‑3 to the heterodimeric receptor complex. CD123 induces the proliferation and differentiation of hemopoietic cells including the pluripotent hematopoietic stem cells as well as a variety of lineage‑committed cells. CD123 has been identified as a potential immunotherapeutic target due to its overexpression in AML compared with normal hematopoietic stem cells.

仕様

• サイズ：10ug
• 種由来：Human
• 発現宿主：Human 293 Cells
• エンドトキシン：Less than 0.1 EU/ug
• タグ：C-hFc
• Target Sequence：Lys20-Arg305
• FormulationLyophilized from a 0.2 um filtered solution of PBS, pH 7.4
• Accession 番号：P26951
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