83-1172-65　Recombinant Human S100 Calcium Binding Protein S100A8/S100A9 Heterodimer （C-His） 10ug　BP103-10ug

特徴

• 背景：S100A8 and S100A9 are pro-inflammatory members of the S100 family of secreted calcium binding proteins. They are produced by neutrophils and monocytes, and forms Ca2+-dependent heterodimer/heterotetramer complexes （known as calprotectin）. Calprotectin （S100A8/A9） is upregulated at sites of inflammation （e.g. psoriasis, rheumatoid arthritis, cardiac ischemia）. It is involved in facilitating leukocyte arachidonic acid trafficking and metabolism, modulation of the tubulin-dependent cytoskeleton during migration of phagocytes and activation of the neutrophilic NADPH-oxidase.

仕様

• サイズ：10ug
• 種由来：Human
• 発現宿主：E. coli
• エンドトキシン：Less than 0.1 ng/ug （1 EU/ug）
• タグ：C-6His
• Target Sequence：M1-E93 ＆ M1-P114
• FormulationSupplied as a 0.2 um filtered solution of 2umM HEPES, 15umM NaCl, 10％ Glycerol, 2.umM EDTA, pH7.4.
• Accession 番号：P05109 ＆ P06702
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