83-1172-39　Recombinant Human Insulin-like Growth Factor Binding Protein 3/IGFBP3 （C-hFc） 10ug　BP068-10ug

特徴

• 背景：Insulin-like growth factor-binding protein 3 （IGFBP3） is a member of IGF binding protein superfamily. IGF binding proteins prolong the half-life of the IGFs and have been shown to either inhibit or stimulate the growth-promoting effects of the IGFs on cell culture. IGFBP3 is expressed by most tissues and the expression levels are higher during development. It is up-regulated in the presence of IGF1, insulin and other growth-stimulating factors such as growth hormone, EGF and phorbol esters. IGFBP3 is the most abundant IGF binding protein in human serum and has been shown to be a growth inhibitory, apoptosis-inducing molecule, capable of acting via IGF-dependent and IGF-independent mechanisms. Several clinical studies have shown that individuals with IGFBP3 levels in the upper range of normal may have a decreased risk for certain common cancers

仕様

• サイズ：10ug
• 種由来：Human
• 発現宿主：Human 293 Cells
• エンドトキシン：Less than 0.1 EU/ug
• タグ：C-hFc
• Target Sequence：G28-K291
• FormulationLyophilized from a 0.2 um filtered solution of PBS, pH7.4
• Accession 番号：P17936
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