83-1172-28　Recombinant Human ErbB2/Her2（C-His） 10ug　BP057-10ug

特徴

• 背景：ErbB2, also known as human epidermal growth factor receptor 2 （HER2）, is a type I membrane glycoprotein that belongs to the epidermal growth factor （EGF） receptor family. ErbB2 is expressed in various tumor tissue including primary breast tumors and tumors from small bowel, esophagus, kidney and mouth. ErbB2 plays a key role in development, cell proliferation and differentiation. ErbB2 is reported to be an orphan receptor, with none of the EGF family of ligands able to activate it. Around 30％ of breast cancers overexpress ErbB2, which is associated with increased disease recurrence and worse prognosis.

仕様

• サイズ：10ug
• 種由来：human
• 発現宿主：Human 293 Cells
• エンドトキシン：Less than 0.1 EU/ug
• タグ：C-6His
• Target Sequence：T23-T652
• FormulationLyophilized from a 0.2 um filtered solution of PBS, pH7.4
• Accession 番号：P04626
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