83-1172-01　Recombinant Mouse B7-1/CD80 （C-His） 10ug　BP013-10ug

特徴

• 背景：CD80, also known as B7-1, is a member of cell surface immunoglobulin superfamily. CD80 is predominately expressed on the surface of antigen-presenting cells including activated B cells, macrophages and dendritic cells. CD80 and CD86, together with their receptors CD28 and CTLA4, form one of the dominant co-stimulatory pathways that mediate T- and B- cell responses. Although both CD28 and CTLA4 can bind to CD80 and CD86, CTLA-4 has 20-100 fold higher affinity than CD28 plays a role in the down-regulation of the immune response. CD80 is also involved in the induction of innate immune responses by activating NF-?B-signaling pathway in macrophages. Therefore, CD80 has the potential to be promising therapeutic targets for autoimmune diseases and various carcinomas.

仕様

• サイズ：10ug
• 種由来：Mouse
• 発現宿主：Human 293 Cells
• エンドトキシン：Less than 0.1 EU/ug
• タグ：C-His
• Target Sequence：Val38-Asn246
• FormulationLyophilized from a 0.2 um filtered solution of PBS, pH7.4
• Accession 番号：Q00609
• この商品は法規制を確認しておりません。（法規制によって販売できない場合もございます）

• 【試薬に関するお問合せ】
• アズワン株式会社 試薬・プロセス材料グループ
• TEL：06-6447-8641
• FAX：06-6447-8642
• E-mail：[email protected]