83-1171-76　Recombinant Human Tau Protein （Mammalian expressed, N-His） 10ug　BP228-10ug

特徴

• 背景：Tau is a microtubule-associated protein expressed primarily in neurons. Tau promotes the assembly and stabilization of microtubules along with other MAP proteins. It is thought that other proteins can compensate for loss of Tau protein function as Tau knockout mice are viable and show no signs of neurodegeneration. There are multiple isoforms of Tau created by alternative splicing of exons 2, 3, and 10. When tau proteins are defective and no longer stabilize microtubules properly, they can result in several neurodegenerative disorders such as Alzheimer's disease, Pick's disease, frontotemporal dementia, cortico-basal degeneration and progressive supranuclear palsy.

仕様

• サイズ：10ug
• 種由来：Human
• 発現宿主：Human Cells
• エンドトキシン：Less than 0.1 EU/ug
• タグ：N-His
• Target Sequence：Ala2-Leu441
• FormulationLyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.
• Accession 番号：P10636-8
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