83-1171-39　Recombinant Human GFRAL-D3 （C-hFc） 500ug　BP1104-500ug

特徴

• 背景：GFR alpha-like is also known as GDNF family receptor alpha-like, GFRAL, C6orf144, UNQ9356, PRO34128. Growth differentiation factor-15 （GDF15） is a circulating protein that has been implicated in multiple biological processes, including energy homeostasis, body weight regulation, and cachexia driven by cancer and chronic disease. GDNF family receptor α-like （GFRAL） was recently identified as the neuronal brainstem receptor responsible for mediating the anorectic actions of GDF15. Brainstem-restricted receptor for GDF15 which regulates food intake, energy expenditure and body weight in response to metabolic and toxin-induced stresses . Upon interaction with its ligand, GDF15, interacts with RET and induces cellular signaling through activation of MAPK- and AKT- signaling pathways

仕様

• サイズ：500ug
• 種由来：Human
• 発現宿主：Human Cells
• エンドトキシン：Less than 1 EU/ug
• タグ：C-Human Fc
• Target Sequence：Cys210-Glu351
• FormulationLyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.
• Accession 番号：Q6UXV0-1
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