83-1170-83　Recombinant Human SIGLEC-8 （C-hFc） 1mg　BP1053-1mg

特徴

• 背景：Siglec-8 is also known as SIGLEC8, SAF2, SIGLEC-8, SIGLEC8L and sialic acid binding Ig like lectin 8. Siglec-8 was first identified by CD33 homology screening of ESTs from a cDNA library generated from a patient diagnosed with idiopathic hypereosinophilic syndrome and was originally termed SAF-2 （sialoadhesin family 2）. At the tissue level, Siglec-8 mRNA was found to be most highly expressed in lung, PBMCs, spleen, and kidney. Two splice variants of Siglec-8 exist. The initially characterized form contains 431 amino acid residues in total, subsequently, a longer form of Siglec-8, initially termed Siglec-8L. Both forms of Siglec-8 are found in eosinophils and contain a V-set domain with lectin activity and two C2-type Ig repeat domains in the extracellular region.

仕様

• サイズ：1mg
• 種由来：Human
• 発現宿主：Human Cells
• エンドトキシン：Less than 1 EU/ug
• タグ：C-Human Fc
• Target Sequence：Met17-Ala363
• FormulationLyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.
• Accession 番号：Q9NYZ4-1
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