83-1170-39　Recombinant Mouse CD70 （C-mFc） 500ug　BP1068-500ug

特徴

• 背景：Cluster of Differentiation 70 （CD70） is also known as CD27 ligand （CD27L / CD27LG）, TNFSF7, TNFSF7G, is a type II transmembrane glycoprotein belonging to the TNF superfamily （TNFSF） and is a surface antigen found on activated T-and B-lymphocytes and mature dendritic cells. Binding of CD70 to its receptor CD27 induces in priming, effector functions, differentiation and memory formation of T-cells, and thus is invloved in the biological processes including T-cell activation, the proliferation of costimulated T-cells, as well as the generation of cytolytic T-cells. CD70 on T cells provides costimulatory signals that are required for T cell proliferation, clonal expansion and the promotion of effector T cell formation. CD70 on mouse B cell has been shown to inhibit terminal differentiation of activated B cells into plasma cells and enhances commitment to memory B cell responses. CD70 induces proliferation and IFNγ production, on NK cells.

仕様

• サイズ：500ug
• 種由来：Mouse
• 発現宿主：Human Cells
• エンドトキシン：Less than 1 EU/ug
• タグ：C-Mouse Fc
• Target Sequence：Gln39-Pro193
• FormulationLyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.
• Accession 番号：P32970-1
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