83-1170-08　Recombinant Human B7-H7 （C-mFc） 500ug　BP1013-500ug

特徴

• 背景：B7-H7 （HHLA2） is a newly identified B7 family member that regulates human T-cell functions. B7-H7 was previously known as human endogenous retrovirus-H long terminal repeat associating 2 （HHLA2） with unidentified function. Recently, B7-H7 has been identified as a specific ligand for human CD28H. The B7-H7-CD28H pathway strongly promoted CD4+ T-cell proliferation and cytokine production via an AKT-dependent signaling cascade in the presence of TCR signaling, suggesting B7-H7 comprises a new co-stimulatory pathway. The first IgV domain of B7-H7, which presumably binds to a putative receptor, shows the highest homology to other B7 family members.

仕様

• サイズ：500ug
• 種由来：Human
• 発現宿主：Human Cells
• エンドトキシン：Less than 1 EU/ug
• タグ：C-Mouse Fc
• Target Sequence：Ile23-Asn344
• FormulationLyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.
• Accession 番号：Q9UM44
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