83-1168-69　Recombinant Human CD275/B7-H2 （C-mFc） 50ug　BP1003-50ug

特徴

• 背景：ICOS ligand （ICOSLG） is also known as B7 homolog 2 （B7-H2）, B7-related protein 1 （B7RP-1） and CD antigen CD275, which belongs to the immunoglobulin superfamily and BTN/MOG family. ICOSLG contains one Ig-like C2-type （immunoglobulin-like） domain and one Ig-like V-type （immunoglobulin-like） domain. Isoform 1 is widely expressed, while isoform 2 is detected only in lymph nodes, leukocytes and spleen. B7-H2 is ligand for the T-cell-specific cell surface receptor ICOS. B7-H2 acts as a costimulatory signal for T-cell proliferation and cytokine secretion and induces also B-cell proliferation and differentiation into plasma cells. B7-H2 could play an important role in mediating local tissue responses to inflammatory conditions, as well as in modulating the secondary immune response by co-stimulating memory T-cell function.

仕様

• サイズ：50ug
• 種由来：Human
• 発現宿主：Human Cells
• エンドトキシン：Less than 1 EU/ug
• タグ：C-Mouse Fc
• Target Sequence：Asp19-Thr256
• FormulationLyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.
• Accession 番号：O75144
• この商品は法規制を確認しておりません。（法規制によって販売できない場合もございます）

• 【試薬に関するお問合せ】
• アズワン株式会社 試薬・プロセス材料グループ
• TEL：06-6447-8641
• FAX：06-6447-8642
• E-mail：[email protected]