83-1168-49　Recombinant Human CD3E （C-hFc） 500ug　BP187-500ug

特徴

• 背景：CD3 epsilon （T-Cell Surface Glycoprotein CD3 Epsilon）, is a single-pass type I membrane glycoprotein, that belongs to the Ig （Immunoglobulin） superfamily. CD3E contains 1 Ig-like domain and 1 ITAM domain. CD3E, together with CD3-gamma, CD3-delta and CD3-zeta, and the T-cell receptor alpha/beta and gamma/delta heterodimers, forms the T cell receptor-CD3 complex. This complex is essential for coupling antigen recognition to several intracellular signal-transduction pathways. The genes encoding the epsilon, gamma and delta polypeptides are located in the same cluster on chromosome 11. The epsilon polypeptide plays an important role in T-cell development. Defects in CD3E gene cause severe immunodeficiency. CD3E gene has also been linked to a susceptibility to type I diabetes in women.

仕様

• サイズ：500ug
• 種由来：Human
• 発現宿主：Human 293 Cells
• エンドトキシン：Less than 0.1 EU/ug
• タグ：C-hFc
• Target Sequence：Asp23-Asp126
• FormulationLyophilized from a 0.2 um filtered solution of PBS, 0.01％Tween 80, pH 7.4
• Accession 番号：P07766
• この商品は法規制を確認しておりません。（法規制によって販売できない場合もございます）

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