83-1168-23　Recombinant Human Syndecan-1/SDC1 （C-His） 10ug　BP176-10ug

特徴

• 背景：Syndecan-1, also known as SDC1 and CD138, is a transmembrane heparan sulfate proteoglycan that belongs to the syndecan proteoglycan family. It is expressed mainly in epithelial cells, but its expression is developmentally regulated during embryonic development. Syndecan-1 has been found to regulate cell adhesion to several ECM molecules, and to play as a co-receptor for fibroblast growth factors, potent angiogenic growth factors involved in differentiation. The expression level of Syndecan-1 is reduced during malignant transformation of various epithelia, and this loss associates with the histological differentiation grade of squamous cell carcinomas, lacking from poorly differentiated tumors. Studies showed in squamous cell carcinomas of the head and neck, positive syndecan-1 expression correlates with a better prognosis.

仕様

• サイズ：10ug
• 種由来：Human
• 発現宿主：Human 293 Cells
• エンドトキシン：Less than 0.1 EU/ug
• タグ：C-6His
• Target Sequence：Gln23-Glu251
• FormulationLyophilized from a 0.2 um filtered solution of PBS, pH7.4.
• Accession 番号：P18827
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