83-1168-01　Recombinant Mouse HVEM/TNFRSF14/TR2/CD270 （C-Fc） 500ug　BP168-500ug

特徴

• 背景：Herpesvirus entry mediator （HVEM） is a type I transmembrane protein that is a member of the TNF receptor superfamily. It is also known as tumor necrosis factor receptor superfamily member 14 and expressed on various immune cells, including T and B cells, NK cells, monocytes, and neutrophils. Interaction of HVEM with TNF family member LIGHT co-stimulates T cells and promotes inflammation. HVEM also triggers inhibitory signaling cascade in effector T （Teff） cells and regulatory T cells （Tregs） as a ligand of B and T lymphocyte attenuator. Therefore, HVEM is considered as a molecular switch, capable of facilitating both stimulatory and inhibitory cosignaling in T cells. It is found that HVEM Ig can activate a significant antiviral effect against HSV-1 infection.

仕様

• サイズ：500ug
• 種由来：Mouse
• 発現宿主：Human 293 Cells
• エンドトキシン：Less than 0.1 EU/ug
• タグ：C-hFc
• Target Sequence：Gln39-Val207
• FormulationLyophilized from a 0.2 um filtered solution of 20mM PB, 150mM NaCl, pH 7.4.
• Accession 番号：Q80WM9
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