83-1167-91　Recombinant Human Complement Factor H-related Protein 1/CFHR1（C-His） 10ug　BP164-10ug

特徴

• 背景：Complement factor H-related protein 1 （CFHR1） is a secreted protein that is a member of the complement factor H protein family. CFHR1 is expressed by hepatocytes and exists as two differentially glycosylated isoforms. The human complement factor H protein family consists of the complement and immune regulators factor H, the factor H-like protein 1（FHL-1） and five factor H-related proteins （CFHR-1 to -5）. Members of the H-related protein family are exclusively composed of individually folded protein domains, termed short consensus repeats （SCRs） or complement control modules. CFHR1 binds to Pseudomonas aeruginosa elongation factor Tuf together with plasminogen, which is proteolytically activated. CFHR1 might mediate complement regulation. It can associate with lipoproteins and may play a role in lipid metabolism. A common CFHR1/CFHR3 genetic deletion has been recognized as being protective against age-related macular degeneration and nephropathy.

仕様

• サイズ：10ug
• 種由来：Human
• 発現宿主：Human 293 Cells
• エンドトキシン：Less than 0.1 EU/ug
• タグ：C-6His
• Target Sequence：Glu19-Arg330
• FormulationLyophilized from a 0.2 um filtered solution of 20mM PB, 150mM NaCl, 0.01％Tween80, pH 7.4
• Accession 番号：Q03591
• この商品は法規制を確認しておりません。（法規制によって販売できない場合もございます）

• 【試薬に関するお問合せ】
• アズワン株式会社 試薬・プロセス材料グループ
• TEL：06-6447-8641
• FAX：06-6447-8642
• E-mail：[email protected]