83-1167-83　Recombinant Human Leukocyte Ig-Like Receptor B1/LILRB1/ILT2/CD85j （C-His） 50ug　BP161-50ug

特徴

• 背景：CD85 antigen-like family member J （CD85J） is an essential mediator of immune activation and tolerance that is the member of the leukocyte immunoglobulin-like receptor （LIR） family. CD85J is primarily expressed on B-cells and monocytes. CD85J is a receptor for a variety of major histocompatibility complex class I molecules （MHCIs） and transduces negative signals and down-regulation of the immune response. The transcription level of CD85J is associated with surface protein expression on NK cells. CD85J can interact with HLA-B or HLA-E and lead to inhibition of the signal triggered by FCER1A and inhibits serotonin release. In addition, CD85J inhibits FCGR1A-mediated phosphorylation of cellular proteins and mobilization of intracellular calcium ions.

仕様

• サイズ：50ug
• 種由来：Human
• 発現宿主：Human 293 Cells
• エンドトキシン：Less than 0.1 EU/ug
• タグ：C-6His
• Target Sequence：Gly24-His458
• FormulationLyophilized from a 0.2 um filtered solution of PBS, pH 7.4
• Accession 番号：Q8NHL6
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