83-1167-71　Recombinant Human ER alpha （N-His） 50ug　BP157-50ug

特徴

• 背景：Estrogen Receptor is a major ligand-activated transcription factor that belongs to the nuclear hormone receptor superfamily. It is widely expressed and acts as a strong activator of estrogen-responsive genes. Estrogen Receptor is composed of several domains essential for hormone binding, DNA binding, and activation of transcription. The protein localizes to the nucleus where it may form a homodimer or a heterodimer with estrogen receptor 2. Estrogen and its receptors are necessary for sexual development and reproductive function, but they also play a role in other tissues such as bone. Estrogen receptors are also involved in pathological processes including breast cancer, endometrial cancer, and osteoporosis.

仕様

• サイズ：50ug
• 種由来：Human
• 発現宿主：E. coli
• エンドトキシン：Less than 0.1 ng/ug （1 EU/ug）
• タグ：N-6His
• Target Sequence：Met1-Gln116
• FormulationSupplied as a 0.2 um filtered solution of 20mM PB, 150mM NaCl, pH 7.2.
• Accession 番号：P03372
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