83-1167-52　Recombinant SARS-CoV-2 NSP8 （C-His） 500ug　BP215-500ug

特徴

• 背景：The replication of coronavirus is operated by a set of non-structural proteins （nsps） encoded by open reading frame 1a （ORF1a） and ORF1ab in its genome. NSP8 is a component of the coronavirus replicase polyprotein that forms a replication complex. It can form a dimer with NSP7 and subsequently assembles into a large hexadecameric structure, which participates in viral replication by acting as a primase. NSP8 was shown to have RNA-dependent RNA polymerase （RdRp） activity that is necessary for producing primers utilized by NSP12 which is normally accepted to be the RdRp for SARS-CoV.

仕様

• サイズ：500ug
• 種由来：SARS-CoV-2
• 発現宿主：E. coli
• エンドトキシン：Less than 0.1 ng/ug （1 EU/ug）
• タグ：C-TEV-8His
• Target Sequence：Ala1-Gln198
• FormulationSupplied as a 0.2 um filtered solution of 20mM Tris, 150mM NaCl, 10％Glycerol, 4mM MgCl2, pH8.0
• Accession 番号：YP_009725304.1
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