83-1167-03　Recombinant Human Cadherin-3/CDH3 （C-His） 500ug　BP126-500ug

特徴

• 背景：Cadherin-3 （CDH3）, also known as placental cadherin, is a single-pass type I membrane protein that belongs to the cadherin superfamily. CDH3 is expressed in some normal epithelial tissues and some carcinoma cell lines. CDH3 is a calcium-dependent cell-cell adhesion glycoprotein comprised of five extracellular cadherin repeats, a transmembrane region, and a highly conserved cytoplasmic tail. It preferentially binds to one another in a homophilic manner. CDH3 plays a role in development, specifically in tissue formation. CDH3 is also involved in the loss of heterozygosity events in breast and prostate cancer. Mutations in CDH3 have been associated with congenital hypotrichosis with juvenile macular dystrophy.

仕様

• サイズ：500ug
• 種由来：Human
• 発現宿主：Human 293 Cells
• エンドトキシン：Less than 0.1 EU/ug
• タグ：C-6His
• Target Sequence：Glu25-Gly654
• FormulationLyophilized from a 0.2 um filtered solution of PBS, pH7.4
• Accession 番号：P22223
• この商品は法規制を確認しておりません。（法規制によって販売できない場合もございます）

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