83-1166-39　Recombinant Cynomolgus CD163 （C-His） 500ug　BP105-500ug

特徴

• 背景：CD163 is a type I transmembrane glycoprotein that belongs to group B of the cysteine-rich scavenger receptor family. The expression of CD163 is essential and is induced by glucocorticoids, IL-10, IL-6, or endotoxin on circulating monocytes, tissue macrophages. CD163 plays an important role in the clearance of hemoglobin-haptoglobin （Hb-Hp） complexes in the liver, spleen and circulation. A soluble form of CD163 exists in plasma, commonly known as sCD163. sCD163 is generated by ectodomain shedding of the membrane-bound receptor. sCD163 is upregulated in a wide range of inflammatory diseases including liver cirrhosis, type 2 diabetes, macrophage activation syndrome, Gaucher's disease, sepsis, HIV infection, rheumatoid arthritis and Hodgkin Lymphoma.

仕様

• サイズ：500ug
• 種由来：Cynomolgus
• 発現宿主：Human 293 Cells
• エンドトキシン：Less than 0.1 EU/ug
• タグ：C-10His
• Target Sequence：M1-S1050
• FormulationLyophilized from a 0.2 um filtered solution of PBS, pH7.4
• Accession 番号：A0A2K5US09
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