83-1164-91　Recombinant Human B7-2/CD86 （C-His） 50ug　BP014-50ug

特徴

• 背景：T-lymphocyte activation antigen CD86 （B7-2） is a type I membrane protein that belongs to the B7 family. CD86 is highly expressed on activated antigen presenting cells. CD86 plays an essential role for T-lymphocyte proliferation and interleukin-2 production through binding CD28 or CTLA-4. It is also involved in the early events of T-cell activation and costimulation of naive T-cells, such as deciding between immunity and anergy that is made by T-cells within 24 hours after activation. Additionally, the CD86 participates innate immune responses by activating NF-?B-signaling pathway in macrophages. CD86 thus is predicted to be a promising candidate for immune therapy.

仕様

• サイズ：50ug
• 種由来：Human
• 発現宿主：Human 293 Cells
• エンドトキシン：Less than 0.1 EU/ug
• タグ：C-His
• Target Sequence：Ala24-Pro247
• FormulationLyophilized from a 0.2 um filtered solution of PBS, pH7.4
• Accession 番号：P42081
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